The National Natural Science Foundation of China notified the first batch of academic misconduct cases this year.

CCTV News:According to the website of the National Natural Science Foundation of China on April 12th, recently, after investigation and deliberation by the Supervision Committee of the National Natural Science Foundation of China and examination and approval by the Committee meeting of the National Natural Science Foundation of China, the National Natural Science Foundation of China has dealt with the subjects involved in related scientific misconduct cases. Now, according to the relevant regulations, the relevant case and handling results will be notified.

　　1. The Supervision Committee of the National Natural Science Foundation of China conducted an investigation on the suspected academic misconduct of Beijing Jianzhu University.

　　After investigation, an online meeting was organized in 2022, and relevant personnel were arranged to collect information on possible fund project evaluation experts. After the meeting, some experts were contacted by the season and others. In 2023, Ji asked a number of potential evaluation experts for the key projects (not funded) he applied for by telephone, SMS and WeChat.

　　There is a problem that interferes with the evaluation order of fund projects in Ji, which violates the agreement in the Commitment Letter of Applicants and Participants of National Natural Science Foundation Projects, and Ji should be responsible for the above problems.

　　After deliberation at the second session of the sixth session of the Supervisory Committee of the National Natural Science Foundation of China and examination and approval at the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to follow Article 44 (1) and (4) and Article 50 (2) of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation Projects. Cancel the application and participation qualification of seasonal national natural science foundation projects for 3 years (December 26, 2023 to December 25, 2026), cancel the evaluation qualification of seasonal national natural science foundation projects for 5 years (December 26, 2023 to December 25, 2028), and give seasonal informed criticism.

　　2. The Supervision Committee of the National Natural Science Foundation of China investigated Yang Lijun’s alleged academic misconduct.

　　After investigation, in the process of applying for the key projects of the National Natural Science Foundation of China for two consecutive years in 2022 and 2023 (both of which were not funded), Yang Lijun asked a number of potential evaluation experts for help by sending emails.

　　Yang Lijun had the problem of asking many possible experts for help for many years, which violated the agreement in the Commitment Letter of Applicants and Participants of the National Natural Science Foundation Project. Yang Lijun should be responsible for the above problems.

　　After deliberation by the Supervision Committee of the Sixth National Natural Science Foundation of China at the second meeting and approval by the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to cancel Yang Lijun’s qualification to apply for and participate in the application of the National Natural Science Foundation of China for three years (from December 26th, 2023 to December 25th, 2026) and give Yang Lijun informed criticism.

　　3. The paper "Jiang" published by the Supervision Committee of the National Natural Science Foundation of China on Chengjiang of Ningxia Medical University
Cheng#, et al. Isovitexin modulates autophagy in Alzheimer’ s disease
via miR-107 signalling. Translational neuroscience. 2022; 13:
407. (Indicate fund number 81960245). "Suspected of academic misconduct conducted an investigation.

　　After investigation, there are some problems in the papers involved, such as buying and selling experimental research data, using others’ signatures without consent, and marking fund projects in scientific research achievements unrelated to science fund projects. Cheng Jiang, the first author, should be responsible for the above problems. In addition, Cheng Jiang included the paper in the progress report of the fund project (approval number 81960245), and Cheng Jiang should also be responsible for this problem.

　　After deliberation at the second session of the sixth session of the Supervisory Committee of the National Natural Science Foundation of China, and examination and approval at the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided that according to Article 47, Article 42, Item 2, Article 43, Items 1 and 8, and Article 46 of the Measures for Investigating and Handling Misconduct in Scientific Research of National Natural Science Foundation Projects, The project of Chengjiang National Natural Science Foundation "TfR1′ s Regulation Mechanism on Mitochondrial Endomembrane Protein frataxin in Neurodifferentiation of Alzheimer’s Disease -iPS Cells" (approval No.81960245) was cancelled, the allocated funds were recovered, and the project application and participation qualification of Chengjiang National Natural Science Foundation were cancelled for five years (from December 26th, 2023 to December 25th, 2028), and it was given to Chengjiang informed criticism.

　　4. The Supervision Committee of the National Natural Science Foundation of China published the paper Xiao by Wang Xiao and Chen Zheling of Hangzhou Medical College.
Wang#, Zheling Chen*, et al. Identification of FOXN4 as a tumor
suppressor of breast carcinogenesis via the activation of TP53 and
deactivation of Notch signaling. Gene. 2020,722:
144057. "(marked with fund number 81802623) was investigated for alleged academic misconduct.

　　After investigation, it was found that the papers involved were bought and sold, and their signatures were used without the consent of the two co-first authors. Wang Xiao, the first author of the papers, and Chen Zheling, the correspondent, should be responsible for the above problems.

　　After deliberation by the Supervision Committee of the Sixth National Natural Science Foundation of China at the second meeting and examination and approval by the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to cancel Wang Xiao’s qualification to apply for and participate in the project of the National Natural Science Foundation of China for five years (from December 26, 2023 to December 25, 2028) in accordance with Article 47, Item 2 of Article 42 and Item 1 of Article 43 of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation of China.

　　Decided to cancel Chen Zheling’s NSFC project "Study on the Mechanism of Rho Mediating Breast Cancer Invasion and Metastasis by Regulating MYH9" (approval No.81802623), recover the allocated funds, and cancel Chen Zheling’s NSFC project application and participation qualification for 3 years (December 26, 2023)

　　5. The Supervision Committee of the National Natural Science Foundation of China conducted an investigation on two papers published by Zhang Zhongqiang and Tan Xiao of Central South University, which were suspected of academic misconduct. The papers involved were as follows:

　　Paper 1: zhongqiang
Zhang, Xiao Tan, JingShan Tong*, et al. The miR-30a-5p/CLCF1 axis
regulates sorafenib resistance and aerobic glycolysis in hepatocellular
Carcinoma. Cell Death & Disease, 2020, 11 (10): 1-14. (The fund number is 81900371).

　　Paper 2: Xiao
Tan, Zhongqiang Zhang, et al. Tim-4 promotes the growth of colorectal
cancer by activating angiogenesis and recruiting tumor-associated
macrophages via the PI3K/AKT/mTOR signaling pathway. Cancer Letters,
2018, 436: 119-128.

　　After investigation, it is found that some of the pictures in Paper 1 are the same as those in many papers of different personnel in many units, but they represent different meanings. The pictures involved are from a third party, so there is a problem of plagiarism in the paper. There are some problems in paper 2, such as improper manipulation of pictures and chaotic use of pictures. Zhang Zhongqiang, the first author of Paper 1, Tong Jingshan, the correspondent, Tan Xiao, the first author of Paper 2, and Tong Jingshan, who provided the pictures involved, should be responsible for the objective results of the problems in the paper respectively.

　　In addition, Zhang Zhongqiang included Paper 1 in the progress report and application form of the fund project (approval number 81900371), and Tan Xiao included Paper 2 in the application form of the fund project (approval number 82002616). Zhang Zhongqiang and Tan Xiao should also be responsible for this issue respectively.

　　After deliberation at the second meeting of the sixth session of the Supervisory Committee of the National Natural Science Foundation of China and examination and approval at the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to follow Articles 47, 40 and 46 of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation Projects. Cancel the project of Zhang Zhongqiang’s National Natural Science Foundation "Study on the Function and Mechanism of mono-DCs, a MBV Regulatory Receptor Containing IL-33, in Inhibiting Chronic Rejection of Heart Transplantation in Mice" (approval No.81900371), recover the allocated funds, cancel Zhang Zhongqiang’s application for the National Natural Science Foundation and participate in the application for five years (from December 26th, 2023 to December 25th, 2028), and give it to Zhang Zhongqiang’s informed criticism.

　　According to Article 40 of the Measures for Investigating and Handling Misconduct in Scientific Research of National Natural Science Foundation of China, it was decided to cancel the project of Tan Xiao National Natural Science Foundation "Study on the Mechanism of BET Degradation Agent Improving the Therapeutic Effect of Colorectal Cancer by Inducing DR5-dependent Cell Killing and Anti-tumor Immunity" (approval number 82002616), recover the allocated funds, and cancel the application and participation qualification of Tan Xiao National Natural Science Foundation for five years (from December 26, 2023 to December 25, 2028).

　　6. The Supervision Committee of the National Natural Science Foundation of China investigated two papers related to Tong Jingshan of Xuzhou Medical University (who worked in Xuzhou Medical University after returning to China) for alleged academic misconduct. The papers involved are as follows:

　　After deliberation by the Supervision Committee of the Sixth National Natural Science Foundation of China at the second meeting and examination and approval by the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to cancel Tong Jingshan’s application and participation in the application for the National Natural Science Foundation of China for five years (from December 26, 2023 to December 25, 2028) and give him informed criticism.

　　7. The Supervision Committee of the National Natural Science Foundation of China published the paper "Ming" by Li Ming of Tongji University.
Li, et al. Overexpression of miR-499-5p inhibits non-small cell lung
cancer proliferation and metastasis by targeting VAV3[J]. Scientific
Reports. 2016; At 6:23100. (marked with fund numbers 81372175 and 81172229), an investigation was conducted on suspicion of academic misconduct.

　　After investigation, there are some problems in the papers involved, such as confusion in the use of pictures, such as duplication within pictures or between pictures, inability to provide all original data, unauthorized marking of other people’s science fund projects, unauthorized use of other people’s signatures, and false correspondence authors and co-authors In addition, another retraction paper by Li Ming (Li
M, et al. PART1 expression is associated with poor prognosis and tumor
recurrence in stage I-III non-small cell lung cancer. J. Cancer 2017;
8(10): 1795-1800.) There are also problems of marking other people’s science fund projects without authorization and using other people’s signatures without consent. Li Ming should be responsible for the above problems.

　　After deliberation by the Supervision Committee of the Sixth National Natural Science Foundation of China at the second meeting and examination and approval by the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to cancel Li Ming’s project application and participation qualification for five years (from December 26, 2023 to December 2028) according to Articles 47, 40, Item 5 of Article 42 and Item 1 and Item 6 of Article 43 of the Measures for Investigating and Handling Misconduct in Scientific Research of National Natural Science Foundation of China.

　　8. The Supervision Committee of the National Natural Science Foundation of China conducted an investigation on two papers published by Shen Sining of Zhengzhou University, which were suspected of academic misconduct. The papers involved were as follows:

　　Paper 1: Si-Ning
Shen*, et al. Down-regulation of long noncoding RNA PVT1 inhibits
esophageal carcinoma cell migration and invasion and promotes cell
apoptosis via microRNA-145-mediated inhibition of FSCN1. Mol Oncol.
2019; 13(12):2554-2573. (Note the fund number 81201954)

　　Paper 2: Si-Ning Shen *, et al.
Silencing lncRNAs PVT1 Upregulates miR-145 and Confers Inhibitory
Effects on Viability, Invasion, and Migration in EC. Mol Ther Nucleic
Acids. 2020; 19:668-682. (Mark fund number 81201954)

　　After investigation, two papers were repeatedly published and tampered with experimental research data and charts; There are also problems of marking other people’s science fund projects without authorization and listing others as paper authors without authorization. Shen Sining, the first and correspondent of two papers, should be responsible for the above problems.

　　After deliberation at the second meeting of the sixth National Natural Science Foundation Committee and examination and approval at the 21st Committee meeting of the National Natural Science Foundation Committee in 2023, it was decided to cancel the application and participation qualification of the National Natural Science Foundation of Shen Si Ning for five years (from December 26, 2023 to 2022) in accordance with Articles 47, 40, Item 1 of Article 42 and Item 1 and Item 6 of Article 43 of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation Projects.

　　9. The Supervision Committee of the National Natural Science Foundation of China conducted an investigation into Wu Yu’s alleged academic misconduct in Fujian Medical University.

　　After investigation, Wu Yu obtained some experimental data and pictures of others in academic exchanges. When writing his application for fund projects in 2023 (application number: 8237100127), he directly marked other people’s experimental data and pictures as experimental results related to the applied projects and wrote them into the application as "research basis". Wu Yu has the problem of copying other people’s research results and forging the research basis of the application, and should be responsible for the above problems.

　　10. The Supervision Committee of the National Natural Science Foundation of China has investigated a number of papers published by Wang Chuanxin of Shandong University on suspicion of academic misconduct, including:

　　Paper 1: Chuan Xin
Wang*, et al. Leptin-mediated regulation of MT1-MMP localization is
KIF1B dependent and enhances gastric cancer cell invasion.
Carcinogenesis, 2013, 34 (5): 974-983. (Note the fund numbers 31270971, 81072406 and 30672010)

　　Paper 2: Chuan Xin
Wang*, et al. Exosome-transmitted miR-128-3p increase chemosensitivity
of oxaliplatin-resistant colorectal cancer. Mol Cancer, 2019,
18(1):43. (Mark fund numbers 81472025 and 81772271)

　　Paper 3: 3：Chuanxin Wang*, et al.
MicroRNA-214 suppresses oncogenesis and exerts impact on prognosis by
targeting PDRG1 in bladder cancer. PLoS ONE, 2015, 10(2):
E0118086. (Note the fund number 81271916)

　　Paper 4: Juan Xin Wang *, et al. mir-203.
Suppresses ZNF217 Upregulation in Colorectal Cancer and Its
Oncogenicity. PLoS ONE.2015, 10(1):
E0116170. (Mark fund numbers 81072406, 81271916, 31270971 and 81301506)

　　Paper 5: Chuan Xin
Wang*, et al. Hypoxia-Inducible MiR-210 Is an Independent Prognostic
Factor and Contributes to Metastasis in Colorectal Cancer. PLoS ONE,
2014, September (3): E 90952. (Note the fund numbers 81271916 and 81301506)

　　Paper 6: Juan Xin Wang *,
et al. Aberrant CCR4 expression is involved in tumor invasion of lymph
node-negative human gastric cancer. PLoS One, 2015, 10(3): e0120059.
(Mark fund numbers 81271916 and 81301506)

　　After investigation, there are some problems in the above papers, such as confusion in the use of pictures and irregular management of experimental raw data (patient follow-up records, etc.). The correspondent Wang Chuanxin and others should be responsible for the problems in the papers involved. In addition, Wang Chuanxin included papers 1, 3 and 5 in the application for fund project (approval number 81772271), paper 1 in the application for fund project (approval number 81472025), paper 2 in the application for fund project (approval number 82130067) and the conclusion report for fund project (approval number 81772271), and paper 3 in the fund project.

　　After deliberation at the second meeting of the sixth session of the Supervisory Committee of the National Natural Science Foundation of China and examination and approval at the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to follow Articles 47, 40 and 46 of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation Projects. The National Natural Science Foundation of Wang Chuanxin’s project "Screening, Verification and Serological Diagnostic Value of lncRNAs Related to Colorectal Cancer" (approval number 81472025) and "Construction and Application Research of Diagnosis and Prognosis Model of Colorectal Cancer Based on Serum Secreted circRNAs" (approval number 81772271) were cancelled. "Model construction and clinical application research of bladder cancer diagnosis and staging prediction based on urine miRNAs differential expression profile" (approval number 81271916) and "Construction of exosomes detection platform based on three-dimensional nano-column array microfluidic chip and basic research on its application in early diagnosis of colorectal cancer" (approval number 82130067), recover the allocated funds of the above four projects, and cancel Wang Chuanxin’s project application and participation qualification for 5 years (in 2023,

　　11. The Supervision Committee of the National Natural Science Foundation of China published a paper "Shuai" on Han Shuai and Li Fuyong of China Medical University.
Han, Fuyong Li*, et al. SETDB1 promotes glioblastoma growth via
CSF-1-dependent macrophage recruitment by activating the AKT/mTOR
Signaling pathway. j expclin cancer RES, 2020, 39 (1): 218. "Suspected academic misconduct was investigated.

　　After investigation, there are many pictures in the papers involved, which are all or part of the same as those in many papers of many units, but they represent different meanings, and there is a problem of confusion in the use of pictures. First author Han Shuai and correspondent Li Fuyong should be responsible for the above problems. In addition, Han Shuai included the related papers in the application form of the fund project (approval number 32200608), Li Fuyong included the related papers in the application form of the fund project (application number 8217102682), and Han Shuai and Li Fuyong should also be responsible for this problem.

　　After deliberation at the second meeting of the sixth National Natural Science Foundation of China, and examination and approval at the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to cancel the Han Shuai National Natural Science Foundation project "Study on Mechanism of Akt Overactivation Promoting Premature Aging" (approval No.32200608), recover the allocated funds, and cancel the application and participation qualification of Han Shuai National Natural Science Foundation for 3 years (.

　　According to Article 40 of the Measures for Investigating and Handling Misconduct in Scientific Research of NSFC Projects, it was decided to cancel the application and participation qualification of NSFC projects in Li Fuyong for three years (from December 26th, 2023 to December 25th, 2026) and give it to informed criticism, Li Fuyong.

　　12. The Supervision Committee of the National Natural Science Foundation of China investigated the suspected academic misconduct of the papers published by Zhang Cong of Jiangnan University. The papers involved are as follows:

　　Paper 1: cong
Zhang*, Toshiyuki Bangi, et al. Evaluation of pseudo-strain hardening
behavior of hybrid fiber reinforced ultra-high performance concrete
containing coarse aggregates by using micromechanical principles.
Journal of Building Engineering, 2022, 61: 105234. (marked with fund number 51908247)

　　Paper 2: cong
Zhang*, Toshiyuki Bangi, et al. Influence of distribution modulus on
the compressive strength of ultra-high-performance concrete with coarse
aggregate (UHPC-CA). Advances in Civil Engineering, 2022, 2022:
7615616. (Mark the fund number 51908247)

　　Paper 3: cong Zhang *, toshiyuki bangi, et al.
Mechanical properties, durability and application of
ultra-high-performance concrete containing coarse aggregate (UHPC-CA): a
review. Construction and Building Materials, 2022, 334:
127360. (Mark the fund number 51908247)

　　Paper 4: cong Zhang *, toshiyuki bangi, et al.
Investigation of SAP content on the shrinkage and tensile properties of
ultra-high performance concrete. Construction and Building Materials,
2022, 345: 128402. (Note the fund number 51908247)

　　Paper 5: cong Zhang *, toshiyuki
Bangi, et al. Influence of eco-friendly fine aggregate on macroscopic
properties, microstructure and durability of ultra-high performance
concrete: a review. Journal of Building Engineering, 2023, 65:
105783. (Mark the fund number 51908247)

　　Paper 6: cong Zhang *, toshiyuki bangi, et al.
Effect of CaCO3 whiskers on tensile properties of ultra-high-performance
engineered cementitious composites. Journal of Building Engineering,
2022, 57: 104896. (Mark the fund number 51908247)

　　Paper 7: cong Zhang *, toshiyuki
Bangi, et al. Experimental study and theoretical modeling for the
flexural property of multi-scale hybrid fiber reinforced SHCC. Case
Studies in Construction Materials, 2022, 16: e01083.（标注基金号51908247）

　　论文8：Cong
Zhang*, Toshiyuki Bangi, et al. Shrinkage and tensile properties of
ultra-high-performance engineered cementitious composites (UHP-ECC)
containing superabsorbent polymers (SAP) and united expansion agent
(UEA). Construction and Building Materials, 2022, 339:
127697. (Mark the fund number 51908247)

　　Paper 9: cong Zhang *, toshiyuki bangi, et al.
Design approach, mechanical properties and cost-performance evaluation
of ultra-high performance engineered cementitious composite (UHP-ECC): a
review. Construction and Building Materials, 2022, 340:
127734. (Mark the fund number 51908247)

　　Paper 10: cong Zhang *, toshiyuki bangi, et al.
Mechanical properties and assessment of a hybrid ultra-high-performance
engineered cementitious composite using calcium carbonate whiskers and
polyethylene fibers. Computers and Concrete, 2022, 30:
339-355.（标注基金号51908247）

　　论文11：Cong Zhang*, Toshiyuki Bangi, et
al. Effect of crushed granite, superabsorbent polymer, and expansive
agent on the workability, compressive properties, and autogenous
shrinkage of ultrahigh-performance concrete. Journal of Materials in
Civil Engineering, 2023, 23: 04023050.（标注基金号51908247）

　　论文12：Zhang
C*, Shen Y, et al. Experimental study and theoretical modeling for the
compressive stress-strain relationship of multi-scale hybrid
fiber-reinforced SHCC. Materiales De Construccion, 2022, 72:
E272. (Indicate fund number 51908247)

　　After investigation, Zhang Cong, the correspondent of Papers 1-11, has the problem of fictional Bangi Toshiyuki of Nanyang Technological University as the signature author of Papers 1-11. Zhang Cong, the first and correspondent of Paper 12, has the problem of fictional Shen Y of Nanyang Technological University as the signed author of Paper 12, and Zhang Cong should be responsible for the above problems.

　　After deliberation at the second meeting of the sixth session of the Supervisory Committee of the National Natural Science Foundation of China and examination and approval at the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to follow the provisions of Article 47 and Item 2 of Article 43 of the Measures for Investigating and Handling Misconduct in Scientific Research of National Natural Science Foundation Projects. The project of Zhang Cong National Natural Science Foundation "Study on High-temperature Bursting Mechanism and Degradation Law of Mechanical Properties of Hybrid Fiber Self-compacting Concrete Tunnel Segments" (approval No.51908247) was cancelled, and the allocated funds were recovered. The project application and participation qualification of Zhang Cong National Natural Science Foundation was cancelled for 3 years (from December 26, 2023 to December 25, 2026), and it was awarded to Zhang Cong informed criticism.

　　13. The Supervision Committee of the National Natural Science Foundation of China investigated the papers published by Liu Zhikui, Liu Qingguang, Tu Kangsheng and Yang Nan of Xi ‘an Jiaotong University on suspicion of academic misconduct. The papers involved are as follows:

　　Paper 1: Zhikui
Liu#, Kangsheng Tu*, Qingguang Liu*, et al. Ftx non coding RNA-derived
miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular
carcinoma. Oncotarget. 2016;
7(18):25350-65. (Mark the fund numbers 81272645, 81402039 and 81572847).

　　Paper 2: Zhikui
Liu#, Kangsheng Tu*, Qingguang Liu*, et al. Methylation-mediated
repression of microRNA-129-2 suppresses cell aggressiveness by
inhibiting high mobility group box 1 in human hepatocellular carcinoma.
European Journal of Medicinal Chemistry.
2018; 145:338-349. (Mark fund numbers 81272645, 81402039, 81502092, 81572847).

　　Paper 3: nan
Yang*, et al. ZKSCAN3 drives tumor metastasis via integrin β 4/FAK/AKT
mediated epithelial– mesenchymal transition in hepatocellular carcinoma.
Cancer Cell International. 2020; 20:216. (Mark fund numbers 81773123 and 81874069).

　　Paper 4: Zhikui
Liu#, Qingguang Liu*, Kangsheng Tu*, et al. MicroRNA-1468 promotes
tumor progression by activating PPAR-γ -mediated AKT signaling in human
hepatocellular carcinoma. Journal of Experimental &Clinical Cancer
Research. 2018; 37(1):49. (Mark the fund numbers 81773123, 81572847 and 81502092).

　　After investigation, papers 1, 2, and 4 have problems such as plagiarism, improper manipulation of pictures, and chaotic use of pictures. Paper 3 has problems such as duplication of pictures from other papers. The first author Liu Zhikui, correspondent Liu Qingguang and co-correspondent Tu Kangsheng of Paper 1, the first author Liu Zhikui, correspondent Liu Qingguang and co-correspondent Tu Kangsheng of Paper 2, the correspondent Yang Nan of Paper 3, the first author Liu Zhikui, correspondent Tu Kangsheng and co-correspondent Liu Qingguang of Paper 4 are respectively responsible for the problems existing in the corresponding papers. In addition, Liu Zhikui should also be responsible for the unauthorized labeling of other people’s fund projects in papers 2 and 4 and the unauthorized use of other people’s signatures in paper 4; Yang Nan should also be responsible for the problem of marking other people’s fund projects without authorization in paper 3; Liu Qingguang, Tu Kangsheng and Liu Zhikui should also be responsible for including the papers involved in the fund project application or the progress and conclusion report.

　　After deliberation at the second session of the sixth session of the Supervisory Committee of the National Natural Science Foundation of China and examination and approval at the 21st Committee meeting of the National Natural Science Foundation of China in 2023, it was decided to follow Articles 47, 40, 43 (1) and 6 (2) of the Measures for Investigating and Handling Misconduct in Scientific Research of National Natural Science Foundation Projects. Cancel the project of Liu Zhikui’s National Natural Science Foundation "Study on the Mechanism of Matrix Hardness Microenvironment Induced Ubiquitin Enzyme USP40 Regulating YAP Signal Pathway to Promote the Growth of Liver Cancer" (approval number 82103428), recover the allocated funds, cancel Liu Zhikui’s National Natural Science Foundation project application and participation qualification for 3 years (December 26, 2023 to December 25, 2026), and give it to Liu Zhikui informed criticism.

　　According to Articles 47, 40 and 46 of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation Projects, Liu Qingguang’s National Natural Science Foundation Project "Molecular Mechanism of Sulphatase 2 Regulating Hepatocellular Carcinoma Tumor Microenvironment through Hedgehog/GLI1 Pathway" (Approval No.81272645) and "Mechanism of VASP Regulating Hepatocellular Carcinoma Invasion and Metastasis in Hypoxic Tumor Microenvironment" (Approval No.81572847) was cancelled, and the allocated funds of the above two projects were recovered, and Liu Qingguang’s National Natural Science Foundation Project application and participation qualification were cancelled for 2 years (.

　　According to Articles 47, 40 and 46 of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation Projects, The TU Kangsheng National Natural Science Foundation Project "Study on the Mechanism of Activation and Secretion of COMP by Hepatic Stellate Cells in the High Hardness Microenvironment of Extracellular Matrix to Promote the Progress of Hepatocellular Carcinoma" (Approval No.81773123) and "Fbxw7 Induces Apoptosis and Growth Arrest of Hepatocellular Carcinoma Cells by Ubiquitin Protease Hydrolysis" (Approval No.81402039) were cancelled, and the allocated funds of the above two projects were recovered, and the application and participation qualification of TU Kangsheng National Natural Science Foundation Project were cancelled for 2 years.

　　It was decided to cancel the application and participation qualification of Yang Nan National Natural Science Foundation for two years (from December 26, 2023 to December 25, 2025) according to Articles 47, 40 and Item 6 of Article 43 of the Measures for the Investigation and Handling of Misconduct in Scientific Research of National Natural Science Foundation Projects, and give it to informed criticism, Yang Nan.

　　14. The Supervision Committee of the National Natural Science Foundation of China conducted an investigation into Li Xiao’s alleged academic misconduct in Shenzhen University.

　　After investigation, Li Xiao made extensive use of other people’s fund project application contents without others’ knowledge, and wrote my own fund project application for 2023 (application number: 8237162197). Li Xiaocun plagiarized and plagiarized the contents of other people’s fund project applications, and Li Xiao should be responsible for the above problems.

　　After deliberation at the second meeting of the sixth National Natural Science Foundation Committee and examination and approval at the 21st Committee meeting of the National Natural Science Foundation Committee in 2023, it was decided to cancel the application of Li Xiao’s 2023 National Natural Science Foundation project "Multivalent MUC1 Glycopeptide Tumor Vaccine Based on Chemical Synthesis" (application number: 8237162197) in accordance with Article 40 of the Measures for Investigating and Handling Misconduct in Scientific Research of National Natural Science Foundation Projects. Li Xiao was disqualified from applying for and participating in the National Natural Science Foundation of China for three years (from December 26th, 2023 to December 25th, 2026), and was criticized by the newspaper.

　　15. The National Natural Science Foundation of China conducted an investigation on Chi Guotai of Dalian University of Technology’s alleged illegal use of funds for science foundation projects.

　　After investigation, Chi Guotai obtained funds for key projects of the National Science Foundation (approval number 71731003) by distributing labor fees to students, which was serious and violated the relevant provisions of the Measures for the Management of Funds for Projects Supported by the National Natural Science Foundation. Chi Guotai, as the project leader, should be responsible for the above problems.

　　After the examination and approval of the first committee meeting of the National Natural Science Foundation of China in 2024, it was decided to cancel the project "Research on Micro-credit Evaluation Theory and Method in Big Data Environment" of the National Natural Science Foundation of Chi Guotai (approval number 71731003) and recover the allocated funds according to item 5 of Article 35 of the Regulations of the National Natural Science Foundation of China and item 4 of Article 45 of the Measures for Investigating and Handling Misconduct in Scientific Research of National Natural Science Foundation of China. Cancel the application and participation qualification of Chi Guotai National Natural Science Foundation for five years (from January 9, 2024 to January 8, 2029) and give it to Chi Guotai informed criticism.